Safe resection margins in breast-conserving surgery

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[Resection margins in conservative breast cancer surgery].

Conservative breast cancer surgery is facing a new problem: the potential tumour involvement of resection margins. This eventuality has been closely and negatively associated with disease-free survival. Various factors may influence the likelihood of margins being affected, mostly related to the characteristics of the tumour, patient or surgical technique. In the last decade, many studies have ...

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Intraoperative ultrasound: improved resection rates in breast-conserving surgery.

AIM The objective of this study was the investigation of a possible improvement of tumor resection rate, i.e. R0 vs. R1 resection when intraoperative ultrasound evaluation of tissue margins is used during breast-conserving surgery (BCS). PATIENTS AND METHODS A total of 250 cases were evaluated retrospectively. The impact of ultrasound analysis onto clean margin rates was evaluated. A subgroup...

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Surgical margins in breast-conserving therapy

Inadequate surgical margins represent a high risk for adverse clinical outcome in breast-conserving therapy (BCT) for early-stage breast cancer. The majority of studies report positive resection margins in 20% to 40% of the patients who underwent BCT. This may result in an increased local recurrence (LR) rate or additional surgery and, consequently, adverse effects on cosmesis, psychological di...

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Breast reconstruction in conserving breast cancer surgery.

Breast conserving treatment (BCT) combined with radiotherapy have proved the test of time as a sound oncological operation regarding survival and local recurrence. Successful BCT is a balance between adequate surgery and maintaining the breast's appearance. Unsatisfactory outcome reaches 20-30% in standard techniques of BCT. Concepts described to widen the spectrum of BCT, have made an improvem...

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Tangential Frozen Section Analysis for the Surgical Margins in Breast-conserving Surgery

Background: The optimal method used to assess surgical margins in breast-conserving surgery (BCS) has not been determined. Method: After wide excision was performed with macroscopic margins of at least 1 cm, surgical margins were evaluated on tangential sections by frozen section analyses (FSA). Positive margins prompted immediate surgical re-excision of the corresponding tissue. The results we...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2017

ISSN: 0923-7534

DOI: 10.1093/annonc/mdx364.003